![]() ![]() Hyperviscosity syndrome can also occur in multiple myeloma patients, and, rarely, in patients with rheumatoid factors and other aggregating proteins. The most common cause of serum hyperviscosity is the presence of large concentrations of IgM monoclonal proteins, and Waldenstrom's macroglobulinemia accounts for 80% to 90% of symptomatic hyperviscosity cases. Although viscosities >1.6 are abnormal, hyperviscosity syndromes are rarely present unless the relative viscosity is >4.0 (approximately). Results are reported as a relative viscosity to water, where normal serum and plasma have a relative viscosity of up to 1.6. Serum, plasma or whole blood viscosity measurements can be useful in patients with hyperviscosity syndromes due to multiple myeloma or Waldenstrom's macroglobulinemia. Viscosity is the property of fluids to resist flow. Lab Name Viscosity, Serum Lab Code SRVISG Epic Ordering
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